Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model
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Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model
The aim of this study was to investigate the in vitro anti-inflammatory activity of Malva sylvestris extract (MSE) and fractions in a co-culture model of cells infected by Aggregatibacter actinomycetemcomitans. In addition, we evaluated the phytochemical content in the extract and fractions of M. sylvestris and demonstrated that polyphenols were the most frequent group in all samples studied. A...
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Given their medical importance, natural products represent a tremendous source of drug discovery. The aim of this study was to investigate Malva sylvestris L. extract and fractions and their pharmacological activities followed by chemical identification. The aqueous fraction (AF) was identified as the bioactive fraction in the in vitro and in vivo assays. The AF controlled the neutrophil migrat...
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Background and Aims: Herbal mouthwashes can improve the oral mucosal wound healing process. Therefore, this study aimed to compare the effect of aqueous extracts of Malva sylvestris and Malva neglecta leaf with common mouthwashes on the oral mucosal wound healing process. Materials and Methods: In this Lab trial, an incision was made into the buccal mucosa of 36 Wistar rats using a surgical bl...
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The isolation and structure of a phytoalexin, malvone A (2-methyl-3-methoxy-5,6-dihydroxy-1,4-naphthoquinone) is reported. Malvone A formation is induced in Malva sylvestris L. by the plant pathogen Verticillium dahliae. In a turbimetric assay for toxicity to V. dahliae, it had an ED50 value of 24 microg/ml. The structure of malvone A was determined by MS and NMR spectroscopy, and by X-ray crys...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0140331